Human milk permeate compositions and methods of making and using same
AssigneeProlacta Bioscience, Inc.
InventorsJoseph FOURNELL, Scott EAKER, Scott ELSTER, David J. RECHTMAN
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Abstract
This disclosure features human milk permeates and compositions containing the same obtained from fractionated whole human milk. The oligosaccharide rich permeate and permeate compositions of the present invention are useful as nutritional supplements for pre-term and full term infants, for establishing or maintaining gut flora and for treating the symptoms of inflammatory bowel disease.
Claims19
A method for promoting development of beneficial gut flora in a subject in need thereof comprising administering to the subject a composition comprising concentrated human milk permeate thereby promoting the development of beneficial gut flora in the subject's gut;
- wherein the concentrated human milk permeate comprises a plurality of human milk oligosaccharides, and wherein the subject is an adult.
A method of making a concentrated human milk permeate composition, comprising,
- (i) removing cream from a pool of human milk comprising a plurality of human milk oligosaccharides to obtain pooled human skim milk;
- (ii) ultra-filtering the pooled human skim milk to obtain human milk permeate, wherein the human milk permeate comprises the plurality of human milk oligosaccharides;
- and
- (iii) concentrating the human milk permeate to increase the concentration of the human milk oligosaccharides;
- thereby making a concentrated human milk permeate composition.
Dependencies are inferred from the claim text.