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AssigneeGuangdong Cell Biotechnology Co., Ltd.
InventorsXinyi SHI, Taihua WANG, Fei PENG, Jing LI
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An application of a transgenic stem cell-derived exosome in preparing a medicament or whitening cosmetic is provided. In the present disclosure, miR-27b-3p is transfected into an epidermal stem cell, and a transgenic stem cell-derived exosome is harvested. It is experimentally verified that the exosome can inhibit the expression of PIK3R3 protein in melanocytes and the proliferation and migration of melanocytes; and safety experiments further demonstrate the safety of the exosome. Therefore, corresponding medicaments or cosmetics prepared from the exosome have excellent medicinal and cosmetic application prospects.
An application of a miR-27b-3p-overexpressing epidermal stem cell-derived exosome in preparing a medicament for inhibiting melanocyte proliferation, wherein the miR-27b-3p-overexpressing epidermal stem cell-derived exosome is prepared according to the following steps:
An application of a miR-27b-3p-overexpressing epidermal stem cell-derived exosome in preparing a cosmetic for inhibiting melanocyte proliferation, wherein the miR-27b-3p-overexpressing epidermal stem cell-derived exosome is prepared according to the following steps:
3-5. (canceled)
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