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US 2023/0190500 A1Published application
Post deployment radial force recovery of biodegradable scaffolds
AssigneeRazmodics LLC
InventorsKamal RAMZIPOOR, Chang Y. LEE
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AssigneeRazmodics LLC
InventorsKamal RAMZIPOOR, Chang Y. LEE
Estimating the term…
Post deployment radial force recovery of biodegradable scaffolds are described where a high molecular weight polymer may be formed into a high molecular weight scaffold by solution casting into a tubular substrate such that the scaffold retains its mechanical properties through processing. The tubular substrate is laser cut and subsequently crimped onto a catheter for deployment into a body lumen. The polymeric scaffold may retain its mechanical properties and result in increased radial strength post-deployment in a saline environment, e.g., within a body lumen. This scaffold enhancement may be attributable at least in part to entanglement of high molecular weight polymer chains as one factor that effects radial force recovery and also to the design or geometry of the scaffold as another factor that effects radial force recovery after deployment.
A scaffold comprising a first radial strength prior to being crimped at a first temperature and a second radial strength when expanded and exposed to an elevated second temperature of at least 37° C. and less than Tg of a polymer making up the scaffold and within a saline environment, wherein the scaffold regains at least 30% of the first radial strength of the scaffold.
A scaffold comprising a tensile strain at yield within a range of 3% to 4% in one or more of the following conditions:
A scaffold comprising a tensile strain at yield within a range of 3% to 4% in one or more of the following conditions:
Dependencies are inferred from the claim text.