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US 2023/0174690 A1Published application
Compositions and methods for single-step multipurpose surface functionalization
AssigneeRutgers, The State University of New Jersey
InventorsEnver Izgu, Zhaojun Jia
Life of this patent
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Abstract
Compositions and methods for functionalizing a variety of surfaces are provided herein. The compositions include compounds of formula (I), which react with azido compounds (R-N3) to form cycloadducts that can spontaneously polymerize on a surface. The R-group in the azido compound can be any molecule of interest, including small molecules and macromolecules
Claims27
A compound of formula (I), or a salt or solvate thereof:
- wherein:
- L is a linker of formula *-X-(Y)ml-Z-, wherein * is the bond between X and the carbon marked as **, wherein:
- X is a bond (null), —C(═O)—, —C(═O)NH—, —C(═O)N(C6—10 aryl)—, —C(═O)N(C2—10 alkenyl)—, or —C(═O)N(C1—10 alkyl)—, wherein the C6-10 aryl is optionally substituted by at least one substituent independently selected from the group consisting of halogen, —R′, —OR′, and —C(═O)OR′;
- each occurrence of Y is independently selected from the group consisting of —CHZCH2O—, —OCH2CH2—, and —CH2CH2—, wherein each CH2 is independently optionally substituted with 1 or 2 CH3 groups;
- Z is —(CH2)m2—, wherein each CH2 is optionally independently substituted with 1 or 2 CH3 groups;
- each occurrence of R′ is independently hydrogen, C2-5 alkenyl, or C1-5 alkyl;
- m1 is 0, 1,2,3,4, 5, 6, 7, 8, 9, or 10;
- m2 is 0, 1, 2, 3, 4, or 5;
- with the proviso that L is not —C(═O)NHCH2—.
6 more elements
(canceled)
11-14. (canceled)
16-17. (canceled)
23-25. (canceled)
27-32. (canceled)
(canceled)
38-40. (canceled)
Dependencies are inferred from the claim text.