Disulfide bond containing compounds and uses thereof
AssigneeThe University of Queensland
InventorsHarendra PAREKH, Kamaker Reddy Tupally
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Abstract
There is provided a range of novel disulfide bond containing compounds. These disulfide bond containing compounds can be used in a variety of applications such as solid phase peptide synthesis, solid phase organic synthesis, formation of dendrimers, formation of macromolecules and formation cyclic peptides; and as a component of a delivery vehicle with a bioactive molecule.
Claims23
A compound of formula XI, or a salt thereof:
- wherein R8 is selected from the group consisting of hydrogen, a counterion, and a substituted or unsubstituted carboxylic acid protecting group;
- and
- R9 and R9′ are independently selected from the group consisting of hydrogen, substituted or unsubstituted C1 to C6 alkyl and a substituted or unsubstituted amine protecting group, or R9 and R9′ together form a substituted or unsubstituted amine protecting group.
The compound according to any one of the preceding claims, wherein at least one of R9 and R9′ are hydrogen.
The compound according to any one of the preceding claims, wherein at least one of OR8, R9 and R9′ are independently replaced by a bond to a complimentary amino acid, a peptide sequence, a bioactive molecule, a lipid, a tag, or a probe.
Dependencies are inferred from the claim text.