Compositions of solid forms of (s)-2-(((s)-6,8-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)amino)-n-(1-(2-methyl-1-(neopentylamino)propan-2-yl)-1h-imidazol-4-yl)pentanamide
AssigneeSpringworks Therapeutics, Inc.
InventorsKristin PATTERSON, Todd Webster SHEARER
Life of this patent
Estimating the term…
Abstract
The present disclosure relates to: a) solid state forms of hydrobromide salts of Compound 1; b) pharmaceutical compositions comprising one or more solid state forms of hydrobromide salts of Compound 1, and, optionally, a pharmaceutically acceptable carrier; c) methods of treating tumors or cancers by administering one or more solid state forms of hydrobromide salts of Compound 1 to a subject in need thereof; and d) methods for the preparation of solid state forms of Compound 1.
Claims21
1-144. (canceled)
A pharmaceutical composition comprising a solid form of nirogacestat or salt thereof wherein the solid form is characterized by a differential scanning calorimetry profile comprising a phase transition between about 39° C. and about 275° C.
Dependencies are inferred from the claim text.