Animal model for studying cancer immunotherapy
AssigneesOncofactory, Centre National de la Recherche Scientifique (CNRS), Universite Claude Bernard Lyon 1, INSERM (Institut Nartional de la Santé et de la Recherche Médicale)
InventorsValérie CASTELLANI, Céline DELLOYE-BOURGEOIS, Clélia Costechareyre, Loraine Jarrosson
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Abstract
The invention relates to a chimeric gallinaceous bird embryo comprising both types of exogenous cells: a. At least one population of cancer cells, and b. At least one population of immune cells, wherein said exogenous cancer cells are present in at least one tissue of said embryo, and said exogenous immune cells are present in at least one tissue of said embryo and/or circulate in the blood vessels of said embryo.
Claims19
Chimeric gallinaceous bird embryo comprising both types of exogenous cells:
- a. At least one population of cancer cells, and
- b. At least one population of immune cells,
- wherein said exogenous cancer cells are present in at least one tissue of said embryo, and said exogenous immune cells are present in at least one tissue of said embryo and/or circulate in the blood vessels of said embryo.
Dependencies are inferred from the claim text.