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US 2023/0101743 A1Published application
Substituted triazine compounds and uses thereof
AssigneeMUSC Foundation for Research Development
InventorsStephen DUNCAN, Juitung LIU, Patrick M. WOSTER, Yuri PETERSON, Steven HOLSHOUSER, Yu-Lin JIANG
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Abstract
The present invention relates to compounds of formula (I): including any stereochemically isomeric form thereof, or pharmaceutically acceptable salts thereof, for the treatment of, for example, hypercholesterolemia.
Claims16
A compound of formula (I):
- wherein:
- X and Y, independently of each other, is halogen, SH, SC(O)CH3, NH-lower alkyl, N(lower alkyl)2, NH-alkoxy or NHNH2;
- Z is hydroxy, halogen, heterocycloalkyl or NR1R2;
- and
- R1 and R2, independently of each other, is hydrogen, alkyl, alkoxy, cycloalkyl, unsubstituted phenyl or phenyl mono-, bi- or tri-substituted independently with NH-phenyl, halogen, hydroxyl, lower alkyl or NH-heteroaryl, wherein said heteroaryl is unsubstituted or mono- or bi-substituted independently with SH or NHCH(CH3)2,
- or a pharmaceutically acceptable salt thereof.
3 more elements
Dependencies are inferred from the claim text.