Compositions comprising amino acids for use in the prevention and treatment of chemotherapy side effects
AssigneeProfessional Dietetics S.R.L.
InventorPaolo Luca Maria GIORGETTI
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Abstract
Composition for use in the prevention and/or in the treatment of cardiotoxicity induced by at least one chemotherapeutic agent in a subject undergoing chemotherapy, the composition comprising an active agent, said active agent containing the amino acids leucine, isoleucine, valine, threonine, lysine and citric acid, succinic acid, malic acid. Said chemotherapeutic agent may be selected in the group consisting of anthracyclines, HER2/ErbB2 inhibitors, tyrosine-kinase inhibitors, vascular endothelial growth factor inhibitors, immune checkpoint inhibitors.
Claims20
A method of treating cardiotoxicity induced by at least one chemotherapeutic agent in a subject undergoing chemotherapy, the method comprising administering to the subject a therapeutically effective amount of an active agent, said active agent containing the amino acids leucine, isoleucine, valine, threonine, lysine and citric acid, succinic acid, malic acid.
A method of treating cardiotoxicity in a subject affected by cancer comprising administering
- a) a therapeutically effective amount of an active agent, said active agent containing the amino acids leucine, isoleucine, valine, threonine, lysine and citric acid, succinic acid, malic acid, and
- b) a therapeutically effective amount of at least one chemotherapeutic agent wherein the active agent and at least one chemotherapeutic agent are administered simultaneously, separately or sequentially.
Dependencies are inferred from the claim text.