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AssigneeUCL Business PLC
InventorsMelissa RAYNER, James PHILLIPS, Jess HEALY, Duncan CRAIG, Gareth WILLIAMS, Ana Rita Marques Pereira TRINDADE, Karolina DZIEMIDOWICZ, Victoria ROBERTON, Holly GREGORY, Desponia ELEFTHERIADOU
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The invention relates to a nanofibrous material comprising a drug for treating a peripheral nerve injury by delivering the drug locally to a damaged or injured nerve. The drug may be such a Non Steroidal Anti Inflammatory Drug or a PPAR agonist. In particular, the invention relates to a drug eluting nerve wrap or bandage that can be wrapped around an injured peripheral nerve. The invention also relates to a nanofibrous drug delivery system or device for delivering a drug locally to a peripheral nerve, a treatment for a peripheral nerve injury comprising contacting a damaged nerve with the drug eluting nanofibrous material or drug delivery system, kits and methods for making the nanofibrous materials, and uses of the nanofibrous materials.
A nanofibrous material comprising a drug, wherein the nanofibrous material comprising the drug is for treating a peripheral nerve injury by delivering the drug locally to a damaged or injured nerve.
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A method of manufacturing a nanofibrous material comprising a drug, wherein the drug is incorporated into the nanofibrous material at an amount suitable to effect sustained release of an efficacious dose when in contact with a nerve in vivo.
A kit for preparing a nanofibrous material comprising a drug, the kit comprising:
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Dependencies are inferred from the claim text.