Medical analysis device with impedance signal processing

Method for classifying a blood sample comprising:

• a) receiving pulse data sets, each pulse data set comprising impedance value data that are associated each time with a time marker, said data together representing a curve of cellular impedance values that are measured when a cell passes through a polarized opening, the cells coming from the blood sample,
• b) for each pulse data set:
• b1. determining a maximum impedance value of the pulse data set,
• b2. calculating a high impedance value by multiplying the maximum impedance value by a high coefficient chosen in the range [0.7;
• 0.95], and by determining in the pulse data set the time markers of which the associated impedance value in the pulse data set is equal to the high impedance value, and by calculating a high duration corresponding to the maximum duration between these time markers, and a low impedance value by multiplying the maximum impedance value by a low coefficient chosen in the range [0.1;
• 0.6], and by determining in the pulse data set the time markers of which the associated impedance value in the pulse data set is equal to the low impedance value, and by calculating a low duration corresponding to the maximum duration between these time markers,
• b3. calculating a peak position value (PP) equal to the division of the difference between the instant associated with the maximum impedance value and the first instant which corresponds to the low impedance value, and the low duration, and optionally a rotation value (WR) equal to the division of the high duration by the low duration,
• c) determining the statistical distribution of the pulse data sets according to low duration/peak position value (PP) pairs or rotation value/peak position value (WR) pairs the statistics being established with respect to a set of ranges of values of pairs (Box 1, Box 2, Box 3, Box 4, Box 5, Box 6, Box 7, Box 8, Box 1′, Box 2′, Box 3′, Box 4′, Box 5′, Box 6′), and
• d) classifying the blood sample by comparing the distribution of the operation c) to a reference distribution of a sample of healthy blood.