Cytometric assays
AssigneeThe Medical Research, Infrastructure, and Heath Services Fund of the Tel Aviv Medical Center
InventorsIlan VOLOVITZ, Merav LUSTGARTEN, Zvi RAM, Netanel Yakov SHAPIRA, Idan BEN HORIN, Gil DIAMANT
Life of this patent
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Abstract
Provided relates to the field of cytometry, specifically to flow cytometric methods and kits for improved diagnosis, prognosis and monitoring of tumors and other lesions involving immune cell infiltration. Further provided are embodiments of the subject matter which relate to compositions and methods providing high resolution quantitative means for immunophenotyping and immune modeling, and for identification of disease prognostic and therapy predictive biomarkers.
Claims20
A kit for identifying innate immune cell populations in a human tissue sample, comprising a fluorescent viability dye and distinct fluorophore-labeled antibodies directed to human CD45, CD11b, CD14, HLA-DR, and CD16;
- and optionally a distinct fluorophore-labeled antibody directed to CD33.
Dependencies are inferred from the claim text.