Composition and method
AssigneeSnoretox Ltd
InventorsThomas McLean, Peter Smooker, Luke Norbury, Peter Coloe, Russell Conduit, Anthony Sasse
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Abstract
The invention relates to a tetanus neurotoxin (TeNT) conjugate comprising a TeNT conjugated to at least one masking moiety (i) through an acid labile linkage or (ii) comprising a masking polypeptide. The invention also relates to a composition comprising the TeNT conjugate and therapeutic use of the TeNT conjugate or composition for treating hypotonia in a subject or enhancing muscle power and/or muscle tone and/or muscle healing and/or sporting performance.
Claims12
A tetanus neurotoxin (TeNT) conjugate comprising a TeNT conjugated to at least one masking moiety:
- (a) through an acid labile linkage;
- or
- (b) the masking moiety comprising a masking polypeptide.
(canceled)
Dependencies are inferred from the claim text.