Methods and compositions for the inhibition of hepatitis b and hepatitis d virus infections
AssigneeReplicor, Inc.
InventorsAndrew VAILLANT, Richard BOULON, Matthieu BLANCHET, Patrick LABONTE
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Abstract
The present disclosure relates to methods for the inhibition of proteins involved in the assembly and or secretion of HBV SVP by inhibiting the activity of casein kinase 1 isoform delta, DNAJB12, and/or microtubule-actin crosslinking factor 1.
Claims23
A composition for the treatment of hepatitis B or hepatitis D infection comprising a pharmaceutically acceptable small molecule inhibiting the activity of at least one of casein kinase 1 isoform delta, DNAJB12, and microtubule-actin crosslinking factor 1, and a carrier.
(canceled)
8-12. (canceled)
A method for the treatment of hepatitis B or hepatitis D infection comprising administering to a subject in need of treatment an effective amount of a pharmaceutically acceptable small molecule inhibiting the activity of casein kinase 1 isoform delta, DNAJB12, and microtubule-actin crosslinking factor 1.
(canceled)
Dependencies are inferred from the claim text.