Antibodies, pharmaceutical compositions and uses thereof
AssigneeObi Pharma, Inc.
InventorsMING-TAIN LAI, JIANN-SHIUN LAI, CHIU-CHUN LIN, I-JU CHEN, WOAN-ENG CHAN
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Abstract
The present invention provides antibodies or the antigen-binding portion thereof, that bind to stage-specific embryonic antigen 3 (SSEA-3) antigen. Also disclosed herein are pharmaceutical compositions and methods for the inhibition of cancer cells in a subject in need thereof. The pharmaceutical compositions include an antibody or an antigen-binding portion thereof and at least one pharmaceutically acceptable carrier.
Claims22
An antibody, or an antigen-binding portion thereof, comprising:
- a heavy chain variable domain comprising an amino acid sequence with 80-100% identity to SEQ ID NO:
- 3;
- and
- a light chain variable domain comprising an amino acid sequence with 80-100% identity to SEQ ID NO:
- 4.
An antibody, or an antigen-binding portion thereof, produced by a hybridoma designated as 1E12b deposited under ATCC Accession Number PTA-126149.
A hybridoma designated as 1E12b deposited under ATCC Accession Number PTA-126149.
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Dependencies are inferred from the claim text.