Replication protein a (rpa)-dna interaction inhibitors

A compound of the formula

• wherein
• R1 is selected from the group consisting of bromo, chloro, iodo, trifluoromethyl, OC(O)-morpholinyl, morpholinyl, furanyl, phenyl, pyridinyl, and isoxazolyl, wherein each hydrogen atom in furanyl, phenyl, pyridinyl, and isoxazolyl is independently optionally substituted with chloro, fluoro, bromo, iodo, C1-C6 haloalkyl, C1-C6 alkyl, or morpholinyl;
• R2 is —OH, —NH—OH, —NH—SO2—R5, —NH(CH2)n-morpholinyl, —NH(CH2)n-piperazinyl, or —NH(CH2)n—(N-methyl-piperazinyl);
• R3 is chloro, fluoro, bromo, or iodo;
• R4 is C1-C6 alkyl;
• R5 is C1-C6 haloalkyl, C1-C6 alkyl, or C3-C6 cycloalkyl, and
• n is 1, 2, 3, or 4;
• or a pharmaceutically acceptable salt thereof;
• and
• with the proviso that the compound is not of the formula
• or a pharmaceutically acceptable salt thereof.