Composition, article and method for affecting a mammal

A method for treating sleeplessness in a mammal, the method comprising the step of administering to such mammal a composition comprising as active ingredients:

• (i) one or more pharmacologically active, non-psychoactive cannabinoids;
• and
• (ii) a pharmacologically active, non-prescription, non-cannabinoid active agent from each of the following subclasses:
• a) amino acid-based ingredients having central nervous system effects;
• b) receptor modulators for acetylcholinesterase, butyrylcholinesterase, 5-HT1 or 5-HT2;
• and
• c) extracts or ground portions (other than such receptor modulators) of a medicinal plant, tree bark or roots;
• and
• (iii) a carrier or matrix in which active ingredients (i) and (ii) are dispersed.

A method for treating anxiety in a mammal, the method comprising the step of administering to such mammal a composition comprising as active ingredients:

• (i) one or more pharmacologically active, non-psychoactive cannabinoids;
• and
• (ii) a pharmacologically active, non-prescription, non-cannabinoid active agent from each of the following subclasses:
• a) amino acid-based ingredients having central nervous system effects;
• b) receptor modulators for acetylcholinesterase, butyrylcholinesterase, 5-HT1 or 5-HT2;
• and
• c) extracts or ground portions (other than such receptor modulators) of a medicinal plant, tree bark or roots;
• and
• (iii) a carrier or matrix in which active ingredients (i) and (ii) are dispersed.

A method for treating pain or inflammation in a mammal, the method comprising the step of administering to such mammal a composition comprising as active ingredients:

• (i) one or more pharmacologically active, non-psychoactive cannabinoids;
• and
• (ii) a pharmacologically active, non-prescription, non-cannabinoid active agent from each of the following subclasses:
• a) amino acid-based ingredients having central nervous system effects;
• b) receptor modulators for acetylcholinesterase, butyrylcholinesterase, 5-HT1 or 5-HT2;
• and
• c) extracts or ground portions (other than such receptor modulators) of a medicinal plant, tree bark or roots;
• and
• (iii) a carrier or matrix in which active ingredients (i) and (ii) are dispersed.