Methods and compositions for the treatment of snake bite
AssigneesLiverpool School of Tropical Medicine, Stichting VU
InventorsNicholas Casewell, Laura-Oana Albulescu, Jeroen Kool
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Abstract
The disclosure herein are materials and methods for the treatment of snake bite. Aspects of the disclosure includes pharmaceutical compositions, and kits, both of which may be of use in the treatment of snake bite.
Claims19
A method of treating snake bite, the method comprising administering to a subject in need of such treatment a combination comprising varespladib and a metalloproteinase inhibitor selected from the group consisting of:
- marimastat and DMPS, in therapeutically effective amounts.
The method according to claim 5, wherein the varespladib and DMPS are provided in the same composition or in separate compositions.
The method according to claim 8, wherein the varespladib, marimastat, and DMPS are provided in the same composition or in separate compositions.
A pharmaceutical composition comprising a therapeutically effective amount of a combination of varespladib and one or both metalloproteinase inhibitors:
- marimastat and DMPS, and a pharmaceutically acceptable carrier.
A kit for treating snake bite, the kit comprising a therapeutically effective amount of a varespladib and one or both metalloproteinase inhibitors:
- marimastat and DMPS.
Dependencies are inferred from the claim text.