Diagnostic Methods and Markers for Bacterial Vaginosis
AssigneeLaboratory Corporation of America Holdings
InventorsCharles Paul Cartwright, Bryndon Denae Lembke, Kalpana Ramachandran
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Abstract
A method of diagnosing bacterial vaginosis in a woman, which involves determining an amount of each of more than one BV-associated bacterium in a vaginal sample obtained from the female and assessing a BV status of the female based on the amount of each of the more than one BV-associated bacterium in the sample
Claims18
A method of detecting positive marker bacterial vaginosis (BV)-associated bacteria, comprising detecting by a polymerase chain reaction (PCR) assay in a gynecological sample obtained from a female in need of BV detection nucleic acid sequences characteristic of the positive marker BV-associated bacteria consisting of BVAB-2, Megasphaera-1, and Atopobium vaginae.
A method of detecting positive marker bacterial vaginosis (BV)-associated bacteria, consisting of detecting by a polymerase chain reaction (PCR) assay in a gynecological sample obtained from a female in need of detection of vaginal microflora alterations nucleic acid sequences characteristic of the positive marker BV-associated bacteria BVAB-2, Megasphaera-1, and Atopobium vaginae.
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