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AssigneeMacroGenics, Inc.
InventorsDavid Lee Farb, Yan Zhou, Krishnan Sampathkumar
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The present invention is directed in part to pharmaceutical compositions for storage and administration comprising a) a HER2/neu antibody (“margetuximab”), b) buffering agents, and c) stabilizers, wherein said margetuximab is stable. The invention in part provides, containers and kits comprising such pharmaceutical compositions. The invention is directed in part to the use of such pharmaceutical compositions, containers, and kits containing margetuximab in the treatment of HER2/neu-positive cancer (i.e., a cancer that expresses HER2), including breast cancer or gastric cancer or GEJ cancer.
1-85. (canceled)
A method of treating cancer in a subject in need thereof, comprising administering a therapeutically effective amount of a margetuximab-comprising pharmaceutical composition to said subject;
Dependencies are inferred from the claim text.