Enhancing expression of line-1 encoded orf2p for cancer therapeutics
OwnerKathleen H. Burnsinventor
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Abstract
Methods for treating a neoplasia are provided. Further provided are novel targets for cancer chemotherapy including ORF2p Protein and methods for increasing expression of ORF2p in neoplasias. Monoclonal antibodies are also provided to various epitopes of ORF2p and their use in research and diagnostivds.
Claims22
A method for treatment of a neoplasia in a cell or population of cells comprising:
- increasing expression of ORF2p in the cell or population of cells.
A method for treatment of a neoplasia in a subject in need thereof, comprising administering to the subject a biologically active agent which increases expression of ORF2p in the neoplasia of the subject.
(canceled)
A monoclonal antibody that specifically binds ORF2p antigenic epitopes.
22-25. (canceled)
Dependencies are inferred from the claim text.