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US 2023/0049100 A1Published application
Method for diagnosis of cancer based on quantitative biomarkers and a database thereof
AssigneeQuanticision Diagnostics Inc.
InventorJiandi ZHANG
Life of this patent
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Abstract
Provided are methods, system and software for diagnosis, prediction and prognosis of a cancer patient based on the quantitative level of a set of biomarkers. Also provided is a database for the purpose of recording the quantitative level of a set of biomarkers.
Claims15
A method of generating a database to provide diagnosis, prediction, or prognosis of cancer, comprising:
- providing a plurality of subjects each having a known clinical outcome of a cancer;
- generating an individual cancer profile (ICP) from each of the plurality of subjects, the individual cancer profile comprising i) a plurality of clinical parameters that each represents a quantitative measurement of a biomarker, wherein the quantitative measurement is from an archived FFPE specimen, continuous, and an absolute amount of the biomarker in the specimen, and ii) a known clinical outcome of a cancer;
- and
- storing the generated individual cancer profiles of the plurality of subjects in the database.
1 more element
A database for providing diagnosis, prediction, or prognosis of cancer comprising a plurality of individual cancer profiles, each generated from a subjects having a known clinical outcome of a cancer, wherein:
- an individual cancer profiles comprises i) a plurality of clinical parameters quantitatively measured from an archived FFPE specimen of the subject and ii) a known clinical outcome of a cancer;
- each of the plurality of clinical parameters represents a quantitative measurement of a biomarker and
- the quantitative measurement is continuous and is an absolute amount of the biomarker in the specimen.
Dependencies are inferred from the claim text.