Nutritional compositions and infant formula for promoting de novo myealination
AssigneeSociete des Produits Nestle S.A.
InventorsNora Schneider, Jonas Hauser, Sean Deoni, Tamas Bartfai
Life of this patent
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Abstract
A synthetic nutritional composition comprising a mineral for use to promote, support or optimise de novo myelination, in particular the de novo myelination trajectory, and/or brain structure, and/or brain connectivity, and/or intellectual potential and/or cognitive potential and/or learning potential and/or cognitive functioning in a subject, in particular a formula fed subject.
Claims16
A method for promoting, supporting or optimizing de novo myelination, the method comprising administering a synthetic nutritional composition comprising a mineral to a formula fed subject.
A method for promoting, supporting or optimizing an outcome selected from the group consisting of de novo myelination trajectory, brain structure, brain connectivity, intellectual potential, cognitive potential, learning potential, cognitive functioning in a human infant or child comprising administering a mineral selected from the group consisting of iron, zinc, copper, calcium, magnesium, and phosphorus and wherein, brain structure refers to the amount and/or spatial distribution of myelinated matter throughout the brain, and/or in specific brain regions, and wherein the cognitive function is optimised if the subject's scores in a standardized neurodevelopmental test are less than one standard deviation different from that of an exclusively breastfed subject of a well-nourished mother.
(canceled)
A synthetic nutritional composition comprising a mineral selected from the group consisting of iron, zinc, copper, magnesium, calcium, phosphorus, and choline and a vitamin, and/or a fatty acid derivative, other than a phospholipid, wherein, if sphingomyelin is present in the composition it is present in an amount of at least 300 mg/kg, wherein if folic acid is present in the composition it is present in amount of at least 100 mcg/kg, wherein if vitamin B12 is present in the composition it is present in amount of at least 5 mcg/100 g, wherein if iron is present in the composition it is present in an amount of at least 5 mg/100 g, wherein if a fatty acid derivative comprising DHA is present in the composition it is present in an amount of at least 60 to 350 mg/100 g, wherein if a fatty acid derivative comprising AA is present in the composition it is present in an amount of at least 60 to 350 mg/100 g wherein all weights are by dry weight of the composition, and wherein the composition is a composition selected from the group consisting of:
- an infant formula, a growing up milk, a composition for infants that is intended to be added or diluted with human breast milk, and a food stuff intended for consumption by an infant and/or child either alone or in combination with human breast milk.
Dependencies are inferred from the claim text.