Crystallized oxalate decarboxylase and methods of use
AssigneeAllena Pharmaceuticals, Inc.
InventorsJack Greene, Richard Johnson, Dennis Krushinskie, Bhami Shenoy
Life of this patent
Estimating the term…
Abstract
Pharmaceutical compositions comprising spray-dried oxalate decarboxylase crystals are disclosed. Methods to treat a disorder associated with elevated oxalate concentration using compositions comprising spray-dried oxalate decarboxylase crystals are also disclosed.
Claims23
A pharmaceutical composition comprising a spray-dried oxalate decarboxylase crystal.
8-38. (canceled)
40-49. (canceled)
A method of reducing oxalate in a mammal, the method comprising administering a pharmaceutical composition comprising a spray-dried oxalate decarboxylase crystal to the mammal in an amount sufficient to reduce the level of oxalate in the urine or blood of the mammal and protect from loss of tissue function.
52-87. (canceled)
89-93. (canceled)
95-98. (canceled)
100-101. (canceled)
A method of preparing a pharmaceutical composition comprising oxalate decarboxylase crystals, wherein the method comprises spray-drying a suspension of oxalate decarboxylase crystals.
103-110. (canceled)
112-133. (canceled)
Dependencies are inferred from the claim text.