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AssigneeMemorial Sloan Kettering Cancer Center
InventorsEric Pamer, Sohn Kim, Peter McKenney, Silvia Caballero
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The present disclosure relates to novel lantibiotics, lantibiotic pharmaceutical compositions, isolated and recombinant lantibiotic-producing bacteria, bacterial pharmaceutical compositions, methods of producing novel lantibiotics from lantibiotic-producing bacteria, and methods of using such lantibiotics, lantibiotic pharmaceutical compositions, and bacterial pharmaceutical compositions to treat gram-positive bacteria infections, including vancomycin resistant enterococci infections, in patients, and to treat food and other objects to avoid gram-positive bacteria contamination.
A pharmaceutical composition comprising a lantibiotic comprising a domain having the amino acid sequence of SEQ. ID. No.:
A method of treating a gram-positive bacteria colonization or infection, the method comprising administering to a patient in need of such treatment, a therapeutically effective amount of a composition comprising a lantibiotic comprising a domain having the amino acid sequence of SEQ. ID. No.:
A bacterial pharmaceutical composition comprising
Dependencies are inferred from the claim text.