Flavonoid and anthocyanin bioproduction using microorganism hosts
AssigneeDebut Biotechnology, Inc.
InventorsJingyi Li, Nicholas Brideau, Joshua Britton, Erik Holtzapple
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Abstract
The invention is directed to methods involved in the production of flavonoids, anthocyanins and other organic compounds. The invention provides cells engineered for the production of flavonoids, anthocyanins and other organic compounds, where the engineered cells include one or more genetic modifications that increase flavonoid production by increasing metabolic flux to flavonoid precursors and/or reducing carbon losses resulting from the production of byproducts.
Claims56
An engineered host cell that comprises one or more genetic modifications resulting in production of flavonoid or anthocyanin from a carbon source that can also be an energy source, through multiple chemical intermediates, by the engineered host cell.
A method of increasing the production of flavonoids or anthocyanins, the method comprising:
- providing an engineered host cell that comprises one or more genetic modifications resulting in production of flavonoid or anthocyanin from a carbon source that can also be an energy source, through multiple chemical intermediates, by the engineered host cell.
A plurality of engineered host cells, wherein each of the plurality of the engineered host cells comprises one or more genetic modifications resulting in production of flavonoid or anthocyanin from a carbon source that can also be an energy source, through multiple chemical intermediates, by the engineered host cells.
A method of increasing the production of flavonoids or anthocyanins, the method comprising:
- providing a plurality of engineered host cells, wherein each of the plurality of the engineered host cell comprises one or more genetic modifications that resulting in production of flavonoid or anthocyanin from a carbon source that can also be an energy source, through multiple chemical intermediates, through multiple chemical intermediates, by the engineered host cell.
Dependencies are inferred from the claim text.