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US 2022/0276259 A1Published application
Methods for diagnosing systemic lupus erythematosus
AssigneeExagen Inc.
InventorsThierry Dervieux, Cole Harris
Life of this patent
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Abstract
The present invention provides methods of diagnosing and monitoring systemic lupus erythematosus.
Claims9
A method for treating systemic lupus erythematosus in a human subject in need thereof, the method comprising:
- (a) measuring a level of erythrocyte-bound C4d (EC4d) marker, B-lymphocyte-bound C4d (BC4d) marker, and anti-nuclear antibody (ANA) in a blood sample obtained from the human subject;
- (b) administering to the human subject an effective amount of cyclophosphamide, a corticosteroid, mycophenolate, methotrexate, azathioprine, leflunomide, belimumab, or hydroxychloroquine to treat systemic lupus erythematosus;
- wherein the human subject is negative for systemic lupus erythematosus based on their level of double-stranded DNA.
Dependencies are inferred from the claim text.