Protein signature for the diagnosis of colorectal cancer and/or pre-cancerous stage thereof
AssigneeAdvanced Marker Discovery, S.L.
InventorsAna Carmen Martín Rodríguez, Rosa Pérez Palacios, Rocío Arroyo Arranz
Life of this patent
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Abstract
The present invention refers to an in vitro method for the diagnosis of colorectal cancer and/or pre-cancerous stage thereof.
Claims20
1-8. (canceled)
A method for detecting a protein biomarker in a biological sample from a subject at risk of developing colorectal cancer or a pre-cancerous stage of colorectal cancer, said method comprising:
- (a) contacting the biological sample with a reagent capable of specifically binding Flt3L and a reagent capable of specifically binding CYFRA21-1;
- and
- (b) measuring level of Flt3L and CYFRA21-1 in the biological sample.
A method for treating a subject having colorectal cancer or a pre-cancerous stage of colorectal cancer, the method comprising administering to the subject a therapy for colorectal cancer or pre-cancerous stage of colorectal cancer, wherein a biological sample from the subject has been determined to have a deviation or a variation in the level of Flt3L and CYFRA21-1 as compared to a control sample.
A kit comprising reagents for determining the level of protein biomarkers Flt3L and CYFRA21-1 and instructions for use.
Dependencies are inferred from the claim text.