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AssigneeWashington State University
InventorsYuehe Lin, Dan Du, Yang Song, Ranfeng Ye
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The disclosure relates to antigen detection reagents and related methods, systems, and kits. The reagents comprise an antigen-binding molecule conjugated to an inorganic component. In some embodiments, the inorganic component possesses catalytic functionality to provide a detectable signal. In some embodiments, the catalytic inorganic component is or comprises a bimetallic nanoparticle. In other embodiments, the inorganic component is a nanoflowers that provides a physical scaffold onto which the antigen-binding component and a reporter component can be loaded, resulting in augmented antigen-binding and reporting capabilities.
1-14. (canceled)
A method of detecting an antigen of interest, comprising:
17-20. (canceled)
An antigen detection reagent, comprising one or more antigen-binding molecules conjugated to a mesoporous bimetallic nanoparticle,
Dependencies are inferred from the claim text.