Depth Filtration Device for Separating Specimen Phases
AssigneeBecton, Dickinson and Company
InventorsKishore K. Bokka Srinivasa Rao, Daniel J. Marchiarullo, Milan Ivosevic
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Abstract
The present disclosure provides a biological fluid collection device, such as a blood collection device, that is adapted to receive a multi-component blood sample having a cellular portion and a plasma portion and quickly, efficiently and cost-effectively separate the plasma portion from the sample. A pressure gradient can be applied across a separation member to facilitate movement of the plasma portion ahead of the cellular portion. The present disclosure allows for both passive and active plasma separation and dispensing.
Claims7
A device for separation of a biological sample into a first phase and a second phase, said device comprising:
- a holder including an inlet and an outlet, said inlet configured for receiving the biological sample;
- at least one lateral flow strip cooperating with the holder for separating the biological sample into the first phase and the second phase;
- and
- a member for creating a pressure gradient across the lateral flow strip to increase a rate of movement of the biological sample through the lateral flow strip such that the first phase exits the flow strip prior to the second phase.
A device for the collection of a biological sample and separation of the biological sample into a first phase and a second phase, said device comprising:
- a collection chamber having an inlet for collecting the biological sample via venous pressure;
- a separation chamber associated with the collection chamber;
- a separator located within the separation chamber for separating the biological sample into the first phase and the second phase;
- a cannula having a first end associated with the separation chamber;
- and
- a vacuum tube associated with the separation chamber via a second end of the cannula, said vacuum tube configured for applying a pressure gradient across the separator to increase a rate of movement of the biological sample through the separator to facilitate separation of the first phase from the second phase and to cause the first phase to enter into the vacuum tube via the cannula.
Dependencies are inferred from the claim text.