Method and system of quantifying lesion evolution

A system for quantifying lesion evolution, comprising a processing circuit configured to:

• acquire a first magnetic resonance, MR, sequence of a portion of a body comprising quantitative information of the portion;
• and
• generate a first MR image representing the portion, based on the first MR sequence, wherein each voxel of the first MR image represents a corresponding volume of the portion;
• and
• determine a lesion evolution value indicating a status of lesion evolution for a voxel of a first region of interest of the first MR image, based on quantitative values of the voxel and a lesion evolution model;
• wherein the lesion evolution model comprises at least two sets of quantitative values, comprising a first set of quantitative values representing the portion of an initial status of lesion evolution, and a second set of quantitative values representing the portion of a final status of lesion evolution;
• wherein a lesion evolution value indicating a status of lesion evolution is associated to each of the at least two sets of quantitative values, wherein a first lesion evolution value indicating the initial status of lesion evolution is associated to the first set of quantitative values, and a second lesion evolution value indicating the final status of lesion evolution is associated to the second set of quantitative values.

A non-transitory computer readable recording medium having computer readable program code recorded thereon which when executed on a device having processing capability is configured to perform operations including:

• acquiring, by a magnetic resonance, MR, scanning device, a first MR sequence of a portion of a body comprising quantitative information of the portion;
• generating, by a processing circuit, a first MR image representing the portion, based on the first MR sequence, wherein each voxel of the first MR image represents a corresponding volume of the portion;
• and
• for a voxel of a first region of interest of the first MR image, determining a lesion evolution value indicating a status of lesion evolution, based on quantitative values of the voxel and a lesion evolution model;
• wherein the lesion evolution model comprises at least two sets of quantitative values, comprising a first set of quantitative values representing the portion of an initial status of lesion evolution, and a second set of quantitative values representing the portion of a final status of lesion evolution;
• and
• wherein a lesion evolution value indicating a status of lesion evolution is associated to each of the at least two sets of quantitative values, wherein a first lesion evolution value indicating the initial status of lesion evolution is associated to the first set of quantitative values, and a second lesion evolution value indicating the final status of lesion evolution is associated to the second set of quantitative values.