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US 2022/0267367 A1Published application
Compositions for the prevention and treatment of parkinson's disease
AssigneeMetselex, Inc.
InventorsWalter Low, Clifford Steer, Michael D. Finch, Cyrus B. Munshi
Life of this patent
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Abstract
Methods of preventing or retarding or reversing or abolishing the onset of Parkinson's and other neurodegenerative diseases are discussed.
Claims4
A compound having the formula (I):
- wherein
- R1 is —OH, or —(PO4), or -L-Dopa,
- R2 is —OH, or —(PO4), or -L-Dopa,
- R3 is —OH, —H or —(PO4),
- R4 is —OH, —(PO4), or -L-Dopa,
- X1 is —H, —OH, —(PO4), or -L-Dopa,
- X2 is —H, —OH, —(PO4), or -L-Dopa
- X3 is —H, —OH, —(PO4), or -L-Dopa,
- X4 is —H, —OH, or -L-Dopa,
- wherein at least one of R1, R2, R4, X1, X2, X3, and X4 is -L-Dopa:
- or a compound having the formula (II)
- wherein
- R1 is —OH, —(PO4), or -L-Dopa,
- R2 is —OH, —(PO4), or -L-Dopa,
- R3 is —OH, —H or —(PO4),
- R4 is —OH, —(PO4), or -L-Dopa,
- R5 is —H, —OH, —(PO4), or -L-Dopa,
- R6 is —H, —OH, —(PO4), gr -L-Dopa,
- R7 is —H, —OH, —(PO4), or -L-Dopa,
- R8 is —H, —OH, —(PO4), ═O, or -L-Dopa,
- R9 is —H, —OH, —(PO4), ═O, or L-Dopa,
- R10 is —H, —OH, —(PO4), or L-Dopa,
- wherein at least one of R1, R2, R4, R5, R6, R7, R8, and R9 is -L-Dopa:
- or a compound having the formula (ITT)
- wherein
- R1 is —OH, —(PO4), or -L-Dopa,
- R2 is —OH, —(PO4), or -L-Dopa,
- R3 is —OH, —H or—(PO4),
- R4 is —OH, —(PO4), or -L-Dopa,
- R5 is —H, —OH, —(PO4), or -L-Dopa,
- R6 is —H, —OH, —(PO4), or -L-Dopa,
- R7 is —H, —OH, —(PO4), or -L-Dopa,
- R8 is —H, —OH, —(PO4), or -L-Dopa,
- R9 is —H, —OH, —(PO4), or -L-Dopa,
- wherein at least one of R1, R2, R4, R5, R6, R7, R8, and R9 is -L-Dopa;
- or a compound having the formula (IV)
- wherein
- R1 is —OH, —(PO4), -or -L-Dopa,
- R2 is —OH, ═O, —(PO4), or -L-Dopa,
- wherein at least one of R1 and R2 is -L-Dopa;
37 more elements
(canceled)
Dependencies are inferred from the claim text.