Provasopressin antagonists and uses thereof
AssigneeWoomera Therapeutics
InventorsWilliam G. North, Roy H.L. Pang
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Abstract
Provided herein are pro-VP antagonists, such as antibodies and antigen-binding portions thereof specific for pro-VP, for identifying and targeting expressing cancer cells. Applicants additionally provide methods of using said compositions, for example to image cancer cells in vivo and in biological samples. The compositions may also be used for treating patients suffering from a provasopressin-expressing cancer. Provasopressin-expressing cancers include neuroendocrine cancer, pancreatic cancer, and prostate cancer.
Claims2
A method of treating a provasopressin-expressing (pro-VP-expressing) cancer, comprising administering a therapeutically effective amount of a provasopressin-binding agent (such as an anti-provasopressin antibody or antigen-binding portion thereof) to a patient in need thereof, wherein the cancer is not small cell lung cancer (SCLC) or breast cancer.
2-52. (canceled)
Dependencies are inferred from the claim text.