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AssigneeUniversity Hospitals Cleveland Medical Center
InventorsDavid Sheyn, Adonis Hijaz, Sangeeta Mahajan
Estimating the term…
A method of diagnosing the risk that a subject has or has an increased risk of developing overactive bladder syndrome is described. The method includes detecting the levels of choline and/or acetylcholine in a biological sample from the subject, comparing the detected levels to reference values, and characterizing the subject as having an increased risk of having or developing overactive bladder syndrome if the choline and/or acetylcholine values are higher than the reference values. Kits for determining choline and/or acetylcholine levels in a subject, and methods of treating a subject for overactive bladder syndrome are also described.
A method of diagnosing the risk that a subject has or has an increased risk of developing overactive bladder syndrome, comprising detecting the levels of choline and/or acetylcholine in a biological sample from the subject, comparing the detected levels to control values, and characterizing the subject as having an increased risk of having or developing overactive bladder syndrome if the choline and/or acetylcholine values are higher than the control values.
A method of treating a subject for overactive bladder syndrome, comprising the step of determining the level of acetylcholine in a biological sample from a subject having overactive bladder syndrome, and treating the subject with a therapeutically effective amount of an anticholinergic agent if the biological sample from the subject is has a higher acetylcholine level than a control value.
A kit for determining choline and/or acetylcholine levels in a subject, comprising a reagent for detecting the level of choline and/or acetylcholine in a biological sample obtained from the subject, and means for signaling the levels of choline and/or acetylcholine detected in the biological sample.
Dependencies are inferred from the claim text.