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US 2022/0206025 A1Published application
Method and apparatus for substrate handling and printing
OwnerIain Stuart MCWILLIAM, Marisa CHONGKWANinventors
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Abstract
The present invention relates to a method and device for manufacturing microarrays, wherein a microarray comprises a plurality of spots, for testing the interaction of biomolecules. Disclosed herein is a method for enhancing efficiency of overlay printing of spot positions on multiple slides or plates arranged in an array wherein a slide or plate order is provided by rows and columns.
Claims13
A method for enhancing efficiency of overlay printing of spot positions on multiple slides arranged in an array comprising the steps:
- printing at least a one spot of a first test material comprising a first type of first potential binding partner pair onto a first row (r1) of slides in an array of n columns in a printing order to provide the first test material on at least slide r1n1 and a replicate slide r1n2
- printing at least one spot of a second test material comprising a second type of first potential binding partner pair onto a second row (r2) of slides in an array of n columns in a printing order to provide a second test material on at least slide r2n1 and a replicate slide r2n2,
- reordering the slides,
- printing spots of at least a first overlay material comprising a first type of second potential binding partner pair to overlay the spots of the at least first test material and/or the spots of the at least second test material wherein when the overlay material is printed, a slide is provided at the same position in the array at which the test material was applied and the overlay material is provided without requiring movement of a printhead between rows when overlaying the first overlay material.
1 more element
Dependencies are inferred from the claim text.