Immunogenic compositions for novel reassortant mammalian ortheovirus from pigs
OwnerWenjun Ma, Liping Wang +1inventors
InventorsWenjun Ma, Liping Wang, Suxiang Tong
Life of this patent
Estimating the term…
Abstract
An immunogenic composition for reducing the incidence or severity of subclinical and clinical signs of orthoreovirus infection is provided. The composition(s) includes at least one segment or portion thereof of orthoreovirus that is derived from a different serotype, host, or strain than at least one other segment or portion thereof. The present disclosure also provides methods for treating, preventing, and reducing the subclinical and clinical signs of orthoreovirus infection in a subject or group of subjects.
Claims75
A composition comprising:
- at least two segments or portions thereof of orothoreovirus, wherein said segment is selected from the group consisting of L1, L2, L3, M1, M2, M3, S1, S2, S3, S4, of orthoreovirus and any combination thereof and wherein said portion thereof is selected from the group consisting of λ1, λ2, λ3, μ1, μ2, σ1, σ2, σ3, μNS, μNSC, σNS, σ1s of orthoreovirus;
- and
- an additional component selected from the group consisting of a stabilizer, an adjuvant, an antimicrobial, an antifungal, a preservative, and any combination thereof;
- wherein at least one segment or portion thereof is from a different serotype, strain, or host than another segment or portion thereof.
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
Dependencies are inferred from the claim text.