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US 2022/0146516 A1Published application
Methods for labeling eukaryotic cells from a multicellular organism as well as for treating and/or diagnosing a cancer using modified monosaccharide compounds
AssigneeDiamidex
InventorSam DUKAN
Life of this patent
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Abstract
The present invention relates to modified monosaccharide compounds implemented in methods for labeling and/or detecting an eukaryotic cell from a multicellular organism. It also relates to such modified monosaccharide compounds implemented in methods for identifying or isolating cancer cells, diagnosing a cancer or for cell therapy.
Claims20
An in vitro method for labeling or detecting or targeting an eukaryotic cell from a multicellular organism, the method comprising the steps of:
- a) contacting a sample comprising eukaryotic cells with at least one modified monosaccharide compound or a precursor thereof;
- b) contacting the sample of step (a) with a compound bearing a first reactive group, optionally in presence of copper;
- and
- c) optionally detecting the compound of step (b) bond to the monosaccharide of step (a), as to detect eukaryotic cells;
- wherein said at least one modified monosaccharide compound has the following formula (I):
- in which X is a second reactive group, the first and the second reactive groups being able to react together in a click chemistry reaction.
3 more elements
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Dependencies are inferred from the claim text.