Bone implants for the treatment of infection
AssigneeSilver Bullet Therapeutics, Inc.
InventorsHoudin DEHNAD, Bohdan Wolodymyr CHOPKO, Paul E. CHIRICO
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Abstract
Described herein are devices, systems and methods for treating disease and/or infection by the release of silver from an implant over an extended period of time. In particular, the devices described herein may be used to treat infections such as osteomyelitis by the controlled release of silver ions from multiple sites of an extended-use implant. This implant typically includes a plurality of arms that both anchor and help distribute the released ions within the tissue. Power may be applied to release the silver ions into the tissue.
Claims18
A method of treating or preventing infection in a bone, the method comprising:
- inserting a silver-releasing implant into a bone in a collapsed configuration;
- expanding the implant into the bone from the collapsed configuration into an expanded configuration having multiple pathways through the bone;
- releasing silver ions from one or more silver reservoirs on the implant into the bone over an extended period of time at a sustained level;
- and
- removing the implant after a predetermined period of time that is longer than a week.
A method of treating or preventing infection in a bone, the method comprising:
- inserting a silver-releasing implant into a bone in a collapsed configuration;
- expanding a plurality of arms from the implant into the bone from the collapsed configuration into an expanded configuration wherein the expanded arms extend in a pattern having multiple pathways through the bone;
- galvanically releasing silver ions from one or more silver reservoirs on the arms into the bone over an extended period of time at a sustained level;
- and
- removing the implant after a predetermined period of time that is longer than a week.
Dependencies are inferred from the claim text.