Methods of Treating Epilepsy via Phosphodiesterase 4 (PDE4) Inhibition
AssigneePath Therapeutics, Inc.
InventorsDeborah Kurrasch, Kingsley Ibhazehiebo
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Abstract
Provided are methods of treating epilepsy. The methods include administering to an individual having epilepsy a therapeutically effective amount of a phosphodiesterase 4 (PDE4) inhibitor. Also provided are methods of identifying an anti-epileptic agent. Such methods include contacting a PDE4 polypeptide with a candidate agent in a PDE4 activity assay, where inhibition of activity of the PDE4 polypeptide by the candidate agent identifies the candidate agent as an anti-epileptic agent.
Claims26
A method of treating epilepsy, comprising administering to an individual having epilepsy a therapeutically effective amount of a phosphodiesterase 4 (PDE4) inhibitor.
A method of identifying an anti-epileptic agent, comprising contacting a phosphodiesterase 4 (PDE4) polypeptide with a candidate agent in a PDE4 activity assay, wherein inhibition of activity of the PDE4 polypeptide by the candidate agent identifies the candidate agent as an anti-epileptic agent.
Dependencies are inferred from the claim text.