Chemically Amplified Detection
AssigneeThe United States of America as represented by the Secretary of the Navy
InventorJoseph R. Hunt
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Abstract
A method is provided for detecting a biological analyte in a medium. The method includes enclosing a catalyst in an encapsulate that includes an associated binder; adding reactants to the medium, followed by adding the encapsulate that contains the encapsulate to the medium. In response to presence of the analyte in the medium, the binder attaches to the analyte and opens the encapsulate to release the catalyst. The catalyst accelerates chemical change of the reactants into products. The method continues by detecting the products to register presence of the analyte.
Claims5
A method for detecting a biological analyte in a medium, said method comprising:
- enclosing a catalyst in an encapsulate that includes an associated binder;
- adding reactants to the medium;
- adding said encapsulate that contains said encapsulate to the medium, wherein
- in response to presence of the analyte in the medium, said binder attaches to the analyte and opens said encapsulate to release said catalyst, which accelerates chemical change of said reactants into products;
- and
- detecting said products to register presence of the analyte.
Dependencies are inferred from the claim text.