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US 2022/0090088 A1Published application
Targeted Nuclear RNA Cleavage and Polyadenylation with CRISPR-Cas
AssigneeUniversity of Rochester
InventorDouglas Matthew Anderson
Life of this patent
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Abstract
The present invention provides proteins, nucleic acids, systems and methods for visualizing or modulating RNA.
Claims30
A fusion protein comprising:
- a) a CRISPR-associated (Cas) protein;
- and
- b) a cleavage or polyadenylation protein.
A fusion protein comprising:
- a) a CRISPR-associated (Cas) protein;
- and
- b) a florescent protein.
A fusion protein comprising:
- a) a CRISPR-associated (Cas) protein;
- and
- b) a nuclear localization signal (NLS).
Dependencies are inferred from the claim text.