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US 2022/0089582 A1Published application
Compounds useful as inhibitors of alcat 1
AssigneePerenna Pharmaceuticals, Inc.
InventorsYuguang SHI, Daqing CHE, Jonathan BAELL, Xiaoyu LIU, Jiasheng FU
Life of this patent
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Abstract
Inhibitors of ALCAT1 are described having the general formula: (I). These compounds offer a treatment for aging and age-related diseases.
Claims6
1-49. (canceled)
50:
- A compound selected from the group consisting of:
51:
- A composition comprising a compound according to claim 50 and a pharmaceutically acceptable carrier, diluent or excipient.
52:
- A method of preparing a pharmaceutical composition comprising admixing a compound according to claim 50 and a pharmaceutically acceptable carrier, diluent, or excipient.
53:
- A method of treating aging or age-related diseases comprising administering to a patient in need of treatment a therapeutically effective amount of a compound according to claim 50.
54:
- A method of treating a disease selected from stroke, ischaemia, and reperfusion injury, comprising administering to a patient in need of treatment a therapeutically effective amount of a compound according claim 50.