Melanocortin Receptor-Specific Peptide Formulations and Methods for Gastrointestinal Tract-Specific Delivery
AssigneePalatin Technologies, Inc.
InventorsJohn Harold Dodd, Stephen Kwaku Dordunoo
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Abstract
Formulations, compositions and methods for delivery of melanocortin receptor-specific peptides, particularly cyclic peptides selective and specific for the melanocortin-1 receptor, to the lumen of the gastrointestinal tract for treatment of melanocortin receptor-mediated or responsive diseases, indications, conditions and syndromes of the gastrointestinal tract.
Claims67
A lower gastrointestinal (GI) tract release pharmaceutical formulation comprising
- a melanocortin receptor-specific peptide or a pharmaceutically acceptable salt thereof disposed within a particle matrix comprising at least one pH-dependent delayed release polymer comprising pH-sensitive methyl methacrylate/methacrylic copolymers selected from the group consisting of Eudragit® L100-55, Eudragit® S100 and Eudragit® FS30D.
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Dependencies are inferred from the claim text.