A new medical treatment for pathologic inflammation

A method for the treatment of a disease resulting from pathologic inflammation, comprising administering a therapeutically effective amount of a compound of formula (I)

• or a pharmaceutically acceptable salt or solvate thereof;
• wherein
• R1 is selected from C1-C6 alkyl and C3-C6 cycloalkyl;
• R2 is selected from H and C1-C3 alkyl;
• R3, R4, R5, and R6 are independently selected from hydrogen, C1-C3 alkyl, C1-C3 alkoxy, C1-C3 alkylthio, and halogen, wherein any alkyl is optionally substituted with one or more fluoro;
• R7 is selected from hydrogen and C1-C3 alkyl;
• and
• R8 and R9 are independently selected from C1-C6 alkyl;
• wherein the treatment also includes administration of a 5-ASA agent selected from mesalazine, sulfasalazine, olsalazine, and balsalazide or a pharmaceutically acceptable salt or solvate thereof.