Calibrating radiological data based on cell distribution

A system for calibrating radiological data associated with a tissue in a subject, the system comprising:

• an interface for receiving a radiological image of the tissue and a microscopy image of the tissue;
• a memory;
• and
• a processor configured to execute instructions stored on the memory to:
• (i) calculate a raw value indicative of a biological parameter in the tissue from the radiological image;
• (ii) to identify a distribution of cells of interest within the tissue from the microscopy image;
• and
• (iii) calculate a calibrated value indicative of a biological parameter of cells of interest within the tissue, by correcting the raw value based on the identified distribution of cells of interest within the tissue.