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US 2022/0064710 A1Published application
Nucleic acid modifying reagents and uses thereof
AssigneePromega Corporation
InventorsCe SHI, Nathan FEIRER, Michael SCURRIA, Subhanjan MONDAL, Said GOUELI, Thomas KIRKLAND, James J. CALI, Poncho MEISENHEIMER
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Abstract
The present disclosure includes compounds, compositions, and methods for nucleic acid amplification reactions. In particular, the present disclosure provides compounds, compositions, and methods for viability PCR (vPCR) applications, in which the compounds that selectively bind to nucleic acids from non-viable cells.
Claims28
A compound or a salt thereof, the compound comprising:
- (A) a nucleic acid binding moiety (“NAB moiety”);
- (B) a live/dead cell differentiating moiety (“LDCD moiety”);
- and
- (C) a nucleic acid modifying moiety (“NAM moiety”).
1 more element
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Dependencies are inferred from the claim text.