Compositions and methods for 3-hydroxypropionic acid production
AssigneeCargill, Incorporated
InventorsHolly JESSEN, Brian RUSH, Jeanette HURYTA, Beth MASTEL, Alan BERRY, Debbie YAVER, Michael CATLETT, Michelle BARNHART
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Abstract
The present application discloses genetically modified yeast cells comprising an active 3-HP fermentation pathway, and the use of these cells to produce 3-HP.
Claims38
A genetically modified yeast cell comprising an active 3-HP fermentation pathway, wherein the cell comprises one or more exogenous 3-HP pathway genes selected from:
- an exogenous PPC gene;
- an exogenous PYC gene;
- an exogenous AAT gene;
- an exogenous ADC gene;
- an exogenous BAAT or gabT gene;
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- an exogenous 3-HPDH gene.
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The genetically modified yeast cell of claim 9, wherein the ADC gene encodes a polypeptide with at least 80% sequence identity to an amino acid sequence selected from SEQ ID NOs:
- 17, 18,133, 135, 137, and 139.
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Dependencies are inferred from the claim text.