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US 2022/0064242 A1Published application
Human hepatocyte growth factor mutant and uses thereof
AssigneeBeijing Northland Biotech. Co., Ltd.
InventorsLiya NIE, Songshan XU, Suyong MA
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Abstract
Disclosed is a human hepatocyte growth factor (hHGF) mutant. Also disclosed are a nucleic acid molecule encoding the mutant, a carrier containing the nucleic acid molecule, and a host cell containing the nucleic acid molecule or the carrier. At the same time disclosed are a pharmaceutical composition comprising the hHGF mutant or the nucleic acid molecule encoding the mutant, and the uses of the hHGF mutant or the nucleic acid molecule encoding the mutant.
Claims19
A mutant of human hepatocyte growth factor (hHGF), which, compared with a natural hHGF, comprises a mutation as follows:
- the amino acid of the natural hHGF at a position corresponding to the 130th position of SEQ ID NO:1 is mutated into an amino acid with a basic side chain.
-12. (canceled)
Dependencies are inferred from the claim text.