Subunit vaccine constructs for flaviviruses
AssigneesRegents of the University of Minnesota, Kanpro Research, Inc.
InventorsSunil A. David, Michael J.H. Brush, Fei Philip Gao
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Abstract
This disclosure describes a subunit vaccine for a flavivirus, methods of making the vaccine, and methods of using the vaccine. The flavivirus may include, is a mosquito-borne flavivirus, for example, Zika virus (ZIKV), dengue virus (DENV), Yellow Fever (YF) virus, and West Nile Virus (WNV). The subunit vaccine may be administered with an adjuvant.
Claims25
A subunit vaccine for a flavivirus, the vaccine comprising an antigen, the antigen comprising a sequence having at least 80% sequence identity to one of SEQ ID NO:1 to SEQ ID NO:12.
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