Pexidartinib risk evaluation and mitigation strategy (rems)

A method comprising:

• receiving, by at least one computing device, data encapsulating a request to fill a prescription for pexidartinib, or a pharmaceutically acceptable salt thereof, for a patient, the request specifying a pharmacy initiating the request and including an identification of the patient;
• polling a server with the pharmacy identification and the patient identification to determine whether
• (i) the pharmacy is registered and pre-approved to fill prescriptions for pexidartinib, or a pharmaceutically acceptable salt thereof;
• (ii) the patient executed a consent form or other acknowledgement associated with the administration of pexidartinib, or a pharmaceutically acceptable salt thereof, and
• (iii) the patient has a patient status form prepared by a prescribing entity transmitted or prepared within a corresponding validity window thereby making such patient status form active, the validity windows increasing in length of days as treatment of the patient with pexidartinib, or a pharmaceutically acceptable salt thereof, progresses;
• transmitting data responsive to the request approving filling of the prescription by the pharmacy if it is determined that the pharmacy is registered and pre-approved to fill prescriptions for pexidartinib, or a pharmaceutically acceptable salt thereof, the patient has executed the consent form or other acknowledgment, and the patient has an active patient status form;
• and
• transmitting data responsive to the request rejecting filling of the prescription by the pharmacy if it is determined (a) that the pharmacy is not registered and pre-approved to fill prescriptions for pexidartinib, or a pharmaceutically acceptable salt thereof, (b) the patient has executed the form, or (c) the patient does not have an active patient status form.